I would probably cut through one of these in no time. That’s why we have spoil boards right ;)!
I’m planning to do this with my spoil board essentially. I have a 2’x4′ cut area that I will divide into zones. The underside will serve as the plenum (where the air is pulled from) and the top side will have zones routed, think perimeter channel around the zone with matrix of channels inside the zone, and several holes for clamping with one passing through to underside. This way I can use mechanical cam clamping and turn off unused zones by plugging one hole.
I think I’d buy an actual vacuum pump though. Shop vacs are sooo loud!
…on my to do list.